Sometimes, the simplest meals are the best, and this Cheese Sandwich Casserole from Betty Crocker is the perfect example of that. It’s an easy-to-make, creamy, cheesy casserole that takes the classic grilled cheese sandwich and transforms it into something even better—baked, bubbly, and totally irresistible. Whether you’re looking for a quick weeknight dinner or a hearty weekend treat, this casserole will hit the spot.

Why You’ll Love This Recipe

Comfort food at its finest – Layers of buttery bread and melted cheese.
Simple ingredients – You probably have everything you need in your kitchen already.
Perfect for leftovers – Enjoy this dish the next day, and it’s just as good.
Crowd-pleaser – This casserole is perfect for family dinners or potlucks.

Ingredients You’ll Need

Here’s a peek at what you’ll need—full details are below!

Bread – White or whole wheat, cut into slices or cubes.
Cheddar cheese – Shredded, for that melty, creamy goodness.
Butter – For richness and flavor.
Milk – To create a creamy base for the casserole.
Eggs – To bind everything together.
Mustard and Worcestershire sauce – For a little tang and depth.

Step-by-Step Directions

Prepare the Bread

Start by cutting the bread into cubes or slices, depending on your preference. You can use day-old bread for added texture, or fresh bread for a softer result. Set aside.

Make the Egg Mixture

In a bowl, whisk together the eggs, milk, mustard, and Worcestershire sauce. Add a pinch of salt and pepper to taste. This mixture will help bind the casserole together while adding flavor.

Layer the Casserole

In a greased casserole dish, layer the bread cubes evenly. Sprinkle a generous amount of shredded cheddar cheese over the top. Repeat the layers until all the bread and cheese are used up.

Pour the Egg Mixture

Pour the egg mixture over the bread and cheese layers. Gently press down the bread to ensure it’s well-soaked with the mixture.

Bake the Casserole

Cover the casserole with foil and bake at 350°F for about 30 minutes. Then, uncover and bake for an additional 15-20 minutes, until the top is golden and bubbly.

Serve and Enjoy

Let the casserole rest for a few minutes before serving. It’s the perfect cheesy, comforting dish!

Expert Tips and Tricks

Use a variety of cheeses – Mix in some mozzarella or Swiss cheese for extra creaminess and flavor.
Add herbs – A sprinkle of dried thyme or oregano will bring extra depth to the casserole.
Don’t skip the rest time – Letting the casserole sit for a few minutes helps the layers set.

Recipe Variations and Possible Substitutions

Add veggies – Layer in some sautéed spinach, tomatoes, or mushrooms for extra flavor.
Spicy twist – Add a few dashes of hot sauce or jalapeños for some heat.
Vegan option – Use dairy-free bread, cheese, and milk for a plant-based version.

Serving and Pairing Suggestions

With a side salad – A fresh green salad balances out the richness of the casserole.
With tomato soup – A classic pairing that’s even better when served together.
With roasted veggies – Roasted broccoli or carrots make for a healthy, savory side.

Storage and Reheating Tips

Fridge – Store leftovers in an airtight container for up to 3 days.
Reheat – Warm up in the oven at 350°F for about 10-15 minutes, or microwave individual portions.
Freezing – This casserole freezes well! Wrap tightly and freeze for up to 3 months.

Frequently Asked Questions

Can I use different types of bread?

Yes! Try sourdough, French bread, or even rye for a different flavor.

Can I make this casserole ahead of time?

Absolutely! Assemble the casserole and refrigerate it for up to 24 hours before baking.

How can I make it more filling?

Add some cooked chicken or bacon between the layers for extra protein.

Can I use pre-shredded cheese?

Yes, but freshly shredded cheese melts better and gives the casserole a smoother texture.

Conclusion

Betty Crocker’s Cheese Sandwich Casserole is the perfect dish for when you need something comforting, easy, and crowd-pleasing. Cheesy, buttery bread with a flavorful twist – it’s a simple yet indulgent dish that everyone will love! Whether you serve it for dinner or as a side dish, it’s sure to be a hit.

Betty Crocker’s Cheese Sandwich Casserole – The Ultimate Comfort Dish

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A creamy, cheesy casserole that takes the classic grilled cheese sandwich and transforms it into something even better—baked, bubbly, and totally irresistible. Perfect for a quick weeknight dinner or a hearty weekend treat.

Author: Touria Elkoudssi
Prep Time: 15 minutes
Cook Time: 45 minutes (30 minutes covered, 15-20 minutes uncovered)
Total Time: 1 hour
Yield: 6–8 servings 1x
Category: Main Dish, Comfort Food
Method: Baking
Cuisine: American
Diet: Vegetarian

Ingredients

Scale

6 slices of bread (white or whole wheat, cut into cubes or slices)
2 cups shredded cheddar cheese
4 tbsp butter
2 cups milk
2 large eggs
1 tbsp mustard
1 tbsp Worcestershire sauce
Salt and pepper to taste

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Instructions

Prepare the Bread: Cut the bread into cubes or slices and set aside.
Make the Egg Mixture: Whisk together eggs, milk, mustard, Worcestershire sauce, salt, and pepper.
Layer the Casserole: In a greased casserole dish, layer bread cubes and shredded cheese, repeating the layers.
Pour the Egg Mixture: Pour the egg mixture over the bread and cheese, pressing down to soak evenly.
Bake the Casserole: Cover with foil and bake at 350°F for 30 minutes. Then, uncover and bake for 15-20 minutes more until golden and bubbly.
Serve and Enjoy: Let the casserole rest before serving.

Notes

Use a variety of cheeses – Add mozzarella or Swiss cheese for extra creaminess.
Add herbs – Fresh or dried thyme or oregano adds flavor.
Resting time – Let the casserole sit for a few minutes to help it set.